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Lecture

Lecture 29

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Department
Biology
Course
BI110
Professor
Louise Dawe
Semester
Fall

Description
BIOLOGY November 27, 2013 Cell Cycle Control (Section 8.5, p. 174) - Cell cycle is controlled by complexes of cyclins with cyclin-dependent protein kinases (CDK) o CKDs only activated when combined with Cyclin - CDKs o Add phosphate groups to target proteins when activated by a cyclin - Different cyclin: CDK combinations regulate cell cycle transitions to different phases of the cycle together with “checkpoints”. Internal Controls - Important internal controls create checkpoints o Ensure that reactions of one stage are complete before cycle proceeds to next stage - These factors alter the activity of cyclin:CDK complexes External Controls - Based on surface receptors that
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