HE101 Lecture Notes - Lecture 9: Antibiotics, Antipsychotic, Antiemetic
Document Summary
Study of drugs: drug properties, mechanisms of action, interactions, classes of drugs, therapeutic use. Multi-disciplinary science: scientific basis, principles for. Drugs: chemical substances that have potential to alter structure and function of our bodies. Drug dynamics (pharmacodynamics: where and how a drug acts on the body, therapeutic effects of drugs e. g. pain relief. Refers to movement of drug into, through and out of the body: absorption, distribution, metabolism, elimination. Drug introduced into body: absorbed into body fluids, distributing to body tissue. Drug binds to receptors: outer membranes, enzymes within cells. Drug action: receptor is turned on or off, agonist vs. antagonist. Drug is metabolized in liver: prepared for excretion. Drug eliminated from body: kidneys, lungs, skin. Drug actions: affect rate of existing biological function, some drugs help to repair damage, some drugs are hormones. Most drug actions are reversible: example: naloxone is carried by paramedics to reverse the effects of heroin (slows down body) in case of patient experiencing overdose.
