PS268 Lecture Notes - Lecture 10: Methadone, Opioid Overdose, Naloxone
Document Summary
Papaver somniferum the poppy that brings sleep. Opiu(cid:373) is produ(cid:272)ed a(cid:374)d a(cid:448)aila(cid:271)le for (cid:272)olle(cid:272)tio(cid:374) for o(cid:374)ly a fe(cid:449) days of the poppy"s pla(cid:374)t"s life ((cid:373)orphi(cid:374)e is naturally produced by the plant) People ate opiu(cid:373) for years, (cid:449)ith (cid:448)ery fe(cid:449) pro(cid:271)le(cid:373)s the(cid:374) they started smoking it (thanks columbus) 1729: opium smoking outlawed in china, but smuggling was widespread. British east india company was involved in opium trade, legally in india and illegally in china. Pressure grew and eventually war broke out between the british and the. 1839-1842; 1856-1860: opium wars are fought, china loses, forced to allow opium sales by the british. Named morphium after morpheus, the god of dreams. Na(cid:373)ed (cid:272)odei(cid:374)e fro(cid:373) the greek (cid:449)ord for (cid:862)poppy head(cid:863) 1853: hypodermic syringe allowed delivery of morphine directly into the blood. Widespread use during war provided relief from pain and dysentery: many veterans were depended on morphine, and dependences was later called (cid:862)soldier"s disease(cid:863) or (cid:862)ar(cid:373)y disease(cid:863)
