Ps280-z lecture 7 tuesday july 30th, 2013. The textbook definition of someone with schizophrenia. Many thoughts would jump from topic to topic without connection between the two. Schizophrenia is a complex disorder: probably many forms, many causes, and my ways that it can happen to a person. Affects a wide range of individuals with a wide range of symptoms. Lifetime prevalence estimates range from 0. 5% to 1% Onset is usually somewhere between the ages of 17 and 35. Less now than before (more around the time of the industrial revolution) Once diagnosed, individuals are less likely to complete their education or maintain a job. High comorbidity rate with depression (~11%) and substance abuse. High rate of suicide in this population. Historical evidence suggests schizophrenia was extremely rare until the late 18th century when there was an apparent surge in cases. Industrialization, obstetric, immunological, and infectious changes may be related to the escalating emergence of this disorder.