PS267 Lecture Notes - Lecture 5: Evoked Potential, Hemoglobin, Positron Emission Tomography

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Electrophysiological methods are used to identify the response characteristics of cells in the visual cortex. Mo(cid:448)i(cid:374)g sti(cid:373)ulus out of sight, (cid:374)euro(cid:374) does(cid:374)"t (cid:272)are for it to fire. Pet fmri: extremely precise spatial info and pretty good timing, noisy, highly sensitive to metal. Provides important tool to imaging neurological pathology. Get differe(cid:374)t ti(cid:373)e (cid:272)ourses depe(cid:374)di(cid:374)g (cid:449)hat state (cid:455)ou"re i(cid:374) Eeg vs erp erp take whole lot of eeg trials and average them together: take total and average, then pull out neural signatures, positive looking waves called negative, negative looking waves called positive/peak. Brai(cid:374) (cid:449)a(cid:448)es (cid:272)ha(cid:374)ge a(cid:272)(cid:272)ordi(cid:374)g to the t(cid:455)pe of sti(cid:373)ulus (cid:455)ou"re looki(cid:374)g at. Erp is(cid:374)"t that fa(cid:374)tasti(cid:272) for spatial i(cid:374)for(cid:373)atio(cid:374) Picks up extremely tiny current emitted by neuron. Measure the blood flow via radioactive isotope. Imaging to look at resonance path of hydrogen via water: atoms aligned, mri force pathway and atoms follow alignment fmri, magnetic properties of blood differ, oxygenated blood vs deoxygenated blood.

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