BIOL 1001 Lecture Notes - Lecture 3: Allele Frequency, Population Genetics, Genetic Drift

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mauvesheep894

10 Feb 2016

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Etymology of key terms gen that which produces hetero different inter between; among intra within; internal mono one; single; alone morph form poly many. Study of genes and genotypes in a population. Want to know: extent of genetic variation, why it exists, how it in maintained, how it changes over the course of many generations. Helps us understand how genetic variation is related to phenotypic variation. Genotype -> set of alleles that determines (in part) the expression of a. Phenotype -> physical (or biochemical) expression of a trait based on genes particular trait. All of the alleles for every gene in a given population. Study genetic variation within the gene pool and how variation changes from. Emphasis is often on variation in alleles between members of a population one generation to the next. Group of individuals of the same species that occupy the same environment.

Related Questions

1. If an individual has a genotype of Bb, what types of gametes (sperm/egg) could they produce?
A) B
B) b
C) B or b
D) Bb, BB, bb
E) Bb

2. Which of the following statements is true about phenotypic plasticity, i.e., phenotype variation that is the result of genotype by environment interactions?
A. Phenotypic plasticity is only favored when the parental environment is a good predictor of the offspring environment
B. Since the trait expression of a genotype varies across environments, it cannot respond to selection
C. A variable environment is required for phenotypic plasticity to be selected for
D. A single trait can only ever be plastic or non-plastic within a species
E. Phenotypic plasticity can only occur within a single generation, never across generations

3. With large numbers of genes contributing to variation for a phenotypic trait (e.g. height in humans), the population approaches what kind of distribution for that trait?
A. Mendelian
B. Exponential
C. Binomial
D. Normal
E. Continuous

4. A classic example of phenotypic plasticity is caste determination in social insects. Whether a female ant becomes a worker, soldier, or queen is determined by the food she is fed. Would you say this this an example of G, E, or GxE?

5. In an infinite population, the frequency of the A allele is 0.3 and the frequency of the a allele is 0.7. What is the frequency of heterozygotes?
A. .10
B. .21
C. .30
D. .42
E. .70

6. Blue eyes are a recessive trait caused by an autosomal allele. If there are 180 people with blue eyes in a population of 500 people, what is the frequency of the brown-eye allele? (Assume HWE)
A. .36
B. .40
C. .50
D. .60
E. .64

7. Imagine flower color in diploid roses is determined by a single gene with two alleles, white and red, which are co-dominant so that heterozygotes are pink. Frank is colorblind and can only discriminate between white and colored roses, and knows that his population has 18 white roses and 182 non-white roses. How many of Frankâs roses are pink? (Assume HWE.)
A. 18
B. 21
C. 42
D. 84
âE. 100

8. Imagine flower color in diploid roses is determined by a single gene with two alleles, white and red, which are co-dominant. If Eva's population has 250 white roses, 500 pink roses, and 250 red roses, what is true about this population?

A. It is not in Hardy-Weinberg equilibrium
B. It is under balancing selection
C. It is connected to another population by migration
D. It is in Hardy-Weinberg equilibrium
ââE. White is a recessive lethal

9. 9% of a population is unable to taste the compound PTC, which is a recessive trait. Assuming HWE, if two carriers of the non-tasting allele had a baby what is the probability that it would be unable to taste PTC?
A. 0.09
B. 0.25
C. 0.30
D. 0.50
E. 0.70

10. (Adapted from: Christensen, A. C. (2000). Cats as an aid to teaching genetics. Genetics, 155(3), 999-1004.) ss cats have no white fur, Ss cats generally have <50% white fur, and SS cats generally have >50% white fur (cats who are 100% white are scored as dominant white and can't be scored for piebald spotting). The S allele is incompletely dominant, but variably expressed, so there is a more-or-less continuous gradient of white pigmentation in populations. You and your friends score all non-white cats up for adoption: http://www.adoptapet.com/cat-adoption/search/50/miles/48824 and find there are 160 with >50% white fur, 350 with <50% white fur, and 490 with no white fur. Which of the following statements is definitely true:

A. The population is in Hardy-Weinberg equilibrium
B. The population is not in Hardy-Weinberg equilibrium
C. There is selection acting on the population
D. It is impossible to know if the population is in Hardy-Weinberg equilibrium
E. Fur color is not a heritable trait and therefore cannot evolve

tanbadger837

What is a genome? What is a genome made of? Describe the bacterial genome. How do bacteria reproduce? What is binary fission? Distinguish between a chromosome and chromatin. Where are chromosomes located in eukaryotic cells? What is the chromosome made of? What is a centromere? What is the centromere's role? What are sister chromatids and how do they arise? Distinguish between somatic cells and germ (gametes) cells. Describe the cell cycle. What are the different phases? What occurs during S phase? What is interphase? How is the cell cycle controlled?

Describe mitosis. What are the phases of mitosis? What occurs in each of the phases of mitosis? What is cytokinesis? How does this differ between plant and animal cells? What is a kinetochore? Where does it form? What is its role? What is the role of microtubules in mitosis? What is a centriole and what is it composed of? What is a centrosome and what is its role in mitosis? What is the metaphase plate and why is this important? What is the mitotic spindle, its role and its makeup? What defines a diploid cell? How many copies of each chromosome is in a diploid cell? What about a haploid cell? Why do the daughter cells of mitosis always have the same complement of chromosomes?

Describe meiosis. What are the phases of meiosis? What occurs in each of the phases of meiosis? Distinguish between meiosis I and meiosis II and describe how each of these processes compare to mitosis. Why do animal cells undergo meiosis? What is a gamete? What is a zygote? What are recombination, crossing-over, and chiasma? When and why does this occur? What is meant by 'homologous pair of chromosomes'? Why don't the daughter cells of meiosis have the same genetic makeup? What controls the segregation of chromosomes into the gametes?

What are genetic characters? What are genetic traits? What is an allele? What is a locus? How many alleles at each locus would a human cell have and why? Distinguish between genotype and phenotype. What is meant by a dominant gene? What is meant by a recessive gene? How do these differ? What is the genotype of a homozygous dominant organism? What is its phenotype? What is the genotype of a homozygous recessive organism? What is its phenotype? What is the genotype of a heterozygous organism? What is its phenotype? What is a genetic cross? Distinguish between the P, F1, and F2 generations. What is a true-breeding line? What is the genotype and phenotype of a cross between homozygous dominant and homozygous recessive parents? If the F1 progeny are crossed, what would be the genotype and phenotype of the F2 generation? What would be the phenotypic ratio? What would be the genotypic ratio? Be ready to generate Punnet square tests or probability analyses of crosses involving more than one genetic locus. Describe a dihybrid cross where two alleles are homozygous dominant in one parent and homozygous recessive in the other. What would be the phenotypic ratio of the F2 generation from this dihybrid cross? What is meant by independent assortment? Be prepared to calculate probabilities resulting from different crosses.

Distinguish between complete and incomplete dominance. How would incomplete dominance alter the results of a hybrid cross? What would the resulting F2 generation phenotype and genotype ratios be? What is codominance? How does this affect the results of crosses? Be prepared to determine likely blood types of parents based on the blood types of their offspring. What is a polygenic trait? What is a carrier state for a genetic disease? What is meant by linked genes? How does this affect expected outcomes of genetic crosses? How is gene linkage used for chromosomal mapping? Distinguish between autosomes and sex chromosomes. What sex chromosomes are found in women? What sex chromosomes are found in men? What are sex-linked traits? Be prepared to give the results of crosses that involve sex-linked recessive traits. What is the process of nondisjunction? What are the likely results? Why is this important? What is a Barr body? Recognize the genetic abnormality of Downs Syndrome, Turner's Syndrome, and Klinefelter's Syndrome.

pucewallaby221

Biology lab homework

Dragon Genes

http://www.concord.org/stem-resources/modern-genetics

BLY 121L - Take HomeAssignment

Due: Start of class time âAt thestart of class next week

Answers MUST beâ¦

â¢ typed (no smaller than 11-pointfont)

â¢ complete sentences (i.e., grammaticallycorrect â AND spell check!)

â¢ THIS IS NOT AGROUP EFFORT â NO POINTS WILL BE AWARDED, IF YOUR PAPER ISSIMILAR IN CONTENT AND WORDING TO THAT OF YOURPEERâS.

Complete ALL4 modules:

1. Intro& Rules

2. Meiosis

3. Pedigree andGenes

4. The PlatesProblem

Complete and answer all of the questions fromeach module.

Introduction

Breed dragons to yield several offspring anddevelop a chart for all of the phenotypic characteristics youobserve.

â¢ Note the genotype and dominant/recessivecondition for each trait.

â¢ When you reach this section of theexercise, be sure to change the genotype for all traits to completethe chart.

Whatare the traits exhibited by yourdragons?

**YOUMUST TURN IN YOURCOMPLETED CHART AND IT MUST BE LEGIBLE!

Rules

Dominance and Recessive Traits

What isthe chromosome number(ânâ) for thedragons?

Which trait(s)exhibit incompletedominance?

What does it mean fora trait to be incompletely dominant?

Noallelic combination is described as being heterozygousrecessive. Why do you thinkthis is thecase?

Some Traits are Sex-linked

Which dragontrait(s)is/are sex-linked?

How dosex-linked traits differ from autosomal traits?

Color and Lethal Combinations

Describehow the inheritance ofcolor is different from that of horns and/orwings.

On whichchromosome is the lethal combination exhibited? What is the lethalcombination?

Meiosis

What is the phenotypeof your new dragon?

Whichtraits areinherited from the mother dragon? AND Which traits are inherited from the father dragon?

Wereany traits expressed by the offspring that differed from either or both of the parents? If so, whatwere they?

How does meiosisallow for variation inoffspring?

How doesfertilization allow for variation in offspring?

Pedigree and Genes

Now that you know how to breed dragons, let'stry some selective breeding in the pedigree view. Use the cross tool tobreed a new generation of dragons; breed two of thedragons from this new (F1) generation. Repeat thisat least8 times.

What do younotice about the dragons as you continue to breed more generations?

Use the chromosome tool to closelyexaminethe dragonsâ genes. If you had trouble answering the sex-linkedquestion above, now you can observe and compare the Xand Y chromosomesâ¦

Can you find any genesthat are different among the members of your F8generation?

How many generationsdo you have to breed until all the dragons are exactly thesame?

You arecreating an inbred strain of dragons in the final generation(s)of this process. Write a notedescribing your strain, and explain what is âspecialâ aboutall individuals in an inbred strain of organisms.

The Plates Problem

Try breedingsome offspring to see resultsof these crosses. Does thepattern of inheritance ofplates tell you anything useful?

Based on yourbreeding experiments, where might you expectto find the gene forplates (i.e., On whichchromosome might the gene be located?) Why do you think this iscorrect?

Dragons thatgrow plates usually do so quite late in their life, so dragons thathave a new baby don't know right away whether or not it will growplates. Which trait(s)exhibited by a baby might helpa mother dragon determine whether her baby will growup to have plates?

DragonGenes
Genotypes/Phenotypes

Trait	Phenotype	Genotype
Horns	Horns
	No Horns
Wings	Wings
	No Wings
Legs	4 Legs
	2 Legs
	No Legs
Tails	Fancy Tail
	Plain Tail
Fire-breathing	Fire-breathing Male
	Non-fire-breathing Male
	Fire-breathing Female
	Non-fire-breathingFemale
Color	Green Male
	Yellow Male
	Red Female
	Blue Female
	Brown Female
	Purple Female

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BIOL 1001 Lecture Notes - Lecture 3: Allele Frequency, Population Genetics, Genetic Drift

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