BIOL 2040 Lecture 4: Chapter 4 Notes and Terms

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Wild-type allele: allele that occurs most frequently, people designate it as normal, in a populatio(cid:374). Does(cid:374)(cid:859)t al(cid:449)a(cid:455)s ha(cid:448)e to (cid:271)e do(cid:373)i(cid:374)a(cid:374)t (cid:894)ofte(cid:374) is(cid:895: wild-type phenotype: wta is responsible for a specific wtp and is used to compare the mutations that are occurring at a particular locus. They had observations that phenotype is under the influence of one or more genes located at specific loci on one or more pairs of homologous chromosomes. The process of mutation is source of alleles. In order for a new allele to be recognized by the organism, it needs to cause change in phenotype. A new phenotype results from the change in functional activity of the cellular product specified by a gene. Sometimes, mutations may enhance the function of the wild-type product. Increases the quantity of the gene product: ex: gain-of-function mutations, most often result in dominant alleles.

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