BIOL 2900 Lecture Notes - Lecture 4: Necrotizing Fasciitis, Endospore, Honduran Lempira
Document Summary
Periplasmic space (metabolism or digestion happens outside the cell for the gram positive cell and you have to secrete molecules for digestion so exotoxins. Harm tissues or trigger host immune responses that cause damage. Endotoxins: can be found in both gram (+) and (-). Molecules found in live bacteria inside the bacterial cell while exotonixs are released but found outside the cell and alive. S. aureus causes abcess, cellulities, invase infection such as lung infection with influenza a, necrotizing fascitis. :many pathogens are developing reistance to multiple drugs, some to nearly all. Hospitals have become hotbeds for highly resistant pthogens like mrsa, increasing the risk that hospitalization kills instead of cures. These are end of the road pathogens that are resistant to last line antimicrobials. Lps (certain activity with gram negative ones released from dead bacteria which is a problem). Lps= lipopolysaccharide structure, has o side chain, core polysaccharide, lipid a (which has outer leafleft out of the outer membrane)
