BIOL 2900 Lecture Notes - Lecture 2: Bcg Vaccine, Tuberculin, Antimicrobial Resistance

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The number of people increase exponentially in the last 200 years. Towards the end of the 18th century small pox vaccine then 2nd vaccine was for rabies. Mid-20th century: antibiotics to fight bacterial cell. These 3 components decreased the incidence of infectious diseases dramatically from. 63% in 1880 to 6% proportion of death today. During the mid 1900s, most scientist and policy makers were shifting their attention away from infectious diseases as better sanitation, vaccines and antibiotics made these diseases rare, at least in the developed world. Vaccination: small pox has been eradicated by mid 1970s, used to kill 3 million people per year. Infectious disease appeared to be out of the way. 1969 surgeon general to congress: it"s time to close the book on infectious diseases. Bacterial cells have been around for 3 billion years, they have evolved over these years to develop antidotes against these antibiotics, we will probably never eradicate all of them.

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