BIOL 4285 Lecture Notes - Lecture 1: Dapi, Exon, Mycin
Document Summary
Feb 10 midterm 1 / march 10 midterm 2 /25% each. Hormones binding to membrane receptors that induces an inner pathway that goes to the nucleus and induces change. Epigenetics: reversible modifications of dna and associated protein that induces changes and can be heritable, usually done by histone modification: acylation causes the histones to become lose and makes the dna become loose. / methylation: tighten up the dna and blocks acylation on these sites. Phosphorylation of serine and threonine to bring other molecules to modify the. Modification to dna the covers epigenetics: methylation at cpg (c connected to g through phosphor). Spatial and temporal consideration: spatial: different positions in our body/ temporal: same time. Rna interference; microrna imp for regulating gene exp. Rna polymerase 2: imp how the polymerase is being dragged down to the dna and how we can regulate it: controlled through: cpg dyad and reverse cpg on the complementary seq.
