BIOL 4370 Lecture Notes - Aplysia Gill And Siphon Withdrawal Reflex, Adenylyl Cyclase, Protein Kinase A
16 Mar 2014
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Nov 14th: synapitic platicicity in aplysia: sea slug. Gill withdrawal reflex: aplysia withdraws when given shock or pinch. Have mechanoreceptors which synapse onto motor neuron which synapse onto gill (causing gill to contract) Gill withdrawal reflex habituates: sensory neuron releases less glutamate with each pinch (learning) Sensitization occurs when you give a shock after pinching over many trials. This axoaxonic synapse causes more glutamate to be released every time there was. After sensitization ap in terminal of sensory neuron from syphon ap is broader and more ca coming in. Ap) leading to more glutmate causing sensitization: rat hippocampus: important in memory. Different regions have excitatory projection that play an important role in memory (increase in synaptic strength) Ca3 pyramidal neurons go to ca1 pyramidal neuron (neurons are called shaffer collaterals) Delivering a tetanus stimuliation in pathway 1 before single shock causes a higher magnitude epsp in single shock in path way 1.
