BIOL 4510 Lecture Notes - Lecture 4: Glycogen, Hemoglobin, Autophagy

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30 Oct 2012
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Some basic cell biology (cid:177) morphology of muscle cells. Although all 3 are capable of contracting, their morphology is quite different. (cid:86)(cid:78)(cid:72)(cid:79)(cid:72)(cid:87)(cid:68)(cid:79)(cid:3) (cid:68)(cid:81)(cid:71)(cid:3) (cid:70)(cid:68)(cid:85)(cid:71)(cid:76)(cid:68)(cid:70)(cid:3) (cid:80)(cid:88)(cid:86)(cid:70)(cid:79)(cid:72)(cid:3) (cid:68)(cid:85)(cid:72)(cid:3) (cid:70)(cid:68)(cid:79)(cid:79)(cid:72)(cid:71)(cid:3) (cid:86)(cid:87)(cid:85)(cid:76)(cid:68)(cid:87)(cid:72)(cid:71)(cid:3) (cid:80)(cid:88)(cid:86)(cid:70)(cid:79)(cid:72)(cid:171)(cid:17)(cid:87)(cid:75)(cid:72)(cid:92)(cid:3) (cid:75)(cid:68)(cid:89)(cid:72)(cid:3) (cid:68)(cid:3) (cid:86)(cid:87)(cid:85)(cid:76)(cid:68)(cid:87)(cid:72)(cid:71)(cid:3) appearance due to the repeat of highly organized structures called sarcomeres along the length of these cells. Sarcomeres are made up of sarcoplasmic reticulum and contractile proteins that are arranged into very organized structures (discussed later) The morphology of skeletal muscle is more complex (more organized) than the other 2 muscle types. Skeletal muscle has 3 layers of connective tissue. Outer epimysium (epi (cid:177) on; mys (cid:177) muscle) The collagen fibers of the epimysium, perimysium and endomysium come together at the end of muscle to form the tendon or aponeurosis (broad sheet of tendon). The muscle is divided into bundles (fascicles) which are surrounded by the perimysium. Each muscle fascicle is divided into muscle fibers. Each skeletal muscle contains 100s (cid:177) 1000s of myofibrils.