KINE 1020 Lecture Notes - Lecture 30: Creatine Supplements, Oxidative Phosphorylation, Phosphocreatine
27 Feb 2017
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Kine 1020 january 16th 2017 metabolism continued. 3 sources of regenerating adp -> atp: phosphocreatine (pcr) = rapid source of atp because one enzyme, oxidative phosphorylationg (mitochondrion) = many enzymes, gylcolysis = more steps but not as fast. Need depends on how fast you need because more complex process = slower. Phosphocreatine: immediate source, lasts only a few seconds at max flux, occurs in cytoplasm, creatine supplements can increase speed and strength. Not much more: does not require oxygen (anaerobic) Glycolysis: uses glucose, at max flux it lasts only a few minutes before muscle fatigue occurs. Not that glucose is loss rather at maximal flux, other processes occur that may cause fatigue: oxygen is not used but pyruvate moves into mitochondrion to support oxidative phosphorylation. Oxidative phosphorylation: uses glucose and fatty, use oxygen to get adp to atp, can support exercise for hours, occurs in mitochondria, aerobic metabolism. The reaction is bi-directional depending on substrate level concentration.
