KINE 2011 Lecture Notes - Lecture 14: Sodium Channel, Cardiac Muscle, Neuromuscular Junction

• School: York University
• Department: Kinesiology & Health Science
• Course: KINE 2011
• Professor: Tanya Da Silva

Document Summary

Tetrodotoxin (pu er sh toxin: blocks voltage gated sodium channels on neurons. The role of voltage gated sodium ion channels in an action potential is to allow for sodium to come into the axon to depolarize the cell and bring it to threshold potential. When you block this gate you get no action potential because you never get up to threshold. This means that you can never open the voltage gated calcium channels at the end of the axon to allow for the release of neurotransmitter. This is why you feel paralysis with this type of poison. On the motor end plate of muscles there is nicotinic acetylcholine receptors. Our motor neurons send signals to our muscles to get them to move when we want them to (consciously, somatic), but even that isn"t fully true. The motor neuron cell body is in the.