KINE 3012 Lecture Notes - Efferent Arteriole, Inulin, Antibody
Document Summary
25 march 25, 13 perritubular but in loop of henle called vaso recta. Glomerulus is essentially looped capillaries -- > eventually blood exits into efferent arteriole. Outside of the basement membrane called a podocyte. Which have a large cell body, foot processes . But don"t have a complete barrier, they have gaps in between. Glomerulus job is to get fluid through the membrane and into the bowman"s capsule (movement of filtrate) Fenestrated means they have a gap in between. Loose ->> more permissive to water and molecules than in the systemic capillaries. Cant pass glomerulus rbcs wbcs large proteins albumins immunoglobulins - too large to fit through. Basement membrane has a lot of negatively charged proteins and plasma tends to be negatively charged. Left with small molecules, ions and water. Overall picture of plasma filtration and fluid reabsorption. 20% leaves the glomerulus leaves to the tubule. Inulin to assess your glomerulus filtration / kidney function.