KINE 3012 Lecture Notes - Lecture 7: Partial Pressure, Hyperpnea, Perfusion
Document Summary
Lower driving pressure for o2 due to less atmospheric pressure. Pressure differences in alveoli leads to gas transfusion. Volume of gas dissolved in a liquid is proportional to the partial pressure of the gas. Cgas = concentration of gas in a liquid (ml/dl) K= solubility coefficient of the gas in the liquid. Important because gases are transmitted between alveoli (air) and blood (liquid) Nitrogen has a greater effect under sea levels. The bends --- come up slowly to acclimate nitrogen because it has high k solubility and the driving pressure is high. Different than increase in respipration that occurs with exercise. Hyperpnea increse ventialtion = increase co2 cproduction: hypoventiatlion. Want to match ventilation (air flow) + perfusion (blood flow q) More blood in bottom of long due to gravity. 1. 4ml o2/ ghb x 15 g hb/ 100 ml blood. = 21 ml o2 / 100 ml blood. 5000 ml blood/min x 21ml o2/ 100 ml blood.