Class Notes (837,548)
Canada (510,312)
York University (35,409)
KINE 1020 (440)

MSD II- Functional limitations.docx

3 Pages
Unlock Document

Kinesiology & Health Science
KINE 1020
Angelo Belcastro

WHO Classification II MSK Functional Limitations Jan 20 MSK II Functional Limitations Description • Sensation of discomfort or pain in SM that occurs following unaccustomed movement/activity • An insult to SM that releases its contents into the circulation (rhabdomyosis) • Muscle proteins are found in the blood • Increases first 24 hrs peaks 24-72 hrs • subsides 5-7 days later Selected Causes of Functional Limitations Non Traumatic Traumatic • increased muscle exertion • crash injuries • heat cramps, conclusions • electric shock • inflammation (primary, secondary) • pressure necrosis (cell damage  death) • drugs • arterial occlusion • genetic conditions • surgery Signs and Symptoms • myalgia, localized pain (site of trauma ) • muscle weakness and swelling • doughy soft feelings in muscles • edema and discoloration • nausea and fever Clinical Assessment • myoglobinemia • creatine kinase – muscle form (CK-MM) • hypocalcaemia • hypophosphatemia • abnormal histology (necrotic areas) • Structural damage Stages 1) initial 2) autogenesis 3) phagocytosis 4) regeneration Initial Stage (first 24hrs) • Muscle tissue disruption (tendons/ligaments) • Loss of function (not reversible in 24-48hrs) • Loss of muscle is noticeable in the muscle (chunks are lost due to rabdomyosis) • Characterizes SM fatigue factors o Lower ATP o Increase in Ca concentrations o Increase ROS Autogenesis Stage • Increased protein breakdown (calpain proteases continues, and ROS made in mitochondria) • Some structure inside the mitochondria is lost • Swelling of sarcoplasmic reticulum – gets bigger • Inflammatory processes o Neutrophil accumulation in muscle o Monocyte and macrophage accumulation  Lysosomes, proteases, myelop
More Less

Related notes for KINE 1020

Log In


Join OneClass

Access over 10 million pages of study
documents for 1.3 million courses.

Sign up

Join to view


By registering, I agree to the Terms and Privacy Policies
Already have an account?
Just a few more details

So we can recommend you notes for your school.

Reset Password

Please enter below the email address you registered with and we will send you a link to reset your password.

Add your courses

Get notes from the top students in your class.