KINE 1020 Lecture Notes - Lecture 5: Hypertrophy

• School: York University
• Department: Kinesiology & Health Science
• Course: KINE 1020
• Professor: Angelo Belcastro

Document Summary

Actin- myosin contractile protein interactions y myosin and actin produce force- source of energy (atp) is needed for the reaction, Myosin atpase hydrolyzes it (breaks down) and mechanical energy (em) is released to cause the reaction, the excess becomes heat energy (eh) y adp with creatine kinase regenerates to produce atp for this reaction to continue. Therefore the cycle can t reproduce as quickly and there is less force produced y: increasing hydrogen ion levels the ph will decrease/ become more acidic- y the more atp the more acidic the muscle ph will be (ex. Capn2/s1 activity in skeletal muscle: influence of heavy exercise y heavy exercise = more protease activity. Chronic impact of fatigue with heavy strength/ resistance exercise y resistance training- you get a change in muscle hypertrophy y endurance training- not much size increase. stimulate satellite cell to new muscle transition: primary inhibitor referred to as myostatin.