KINE 2011 Lecture Notes - Renal Function, Aldosterone, Resting Potential
Document Summary
Angiotensin ii has direct effect on controlling peripheral circulation and also glomerular filtration through afferent arteriole. Also stimulates production of vasopressin from the hypothalamus. That allows it to have more broad reaching effect. t. Angiotensin ii activates adrenal cortex to produce aldosterone which produces significant effects on kidney. How potassium ions are regulated: k+ is filtered, k+ also secreted *** Doesn"t stay there forever, the potassium channels allow it to leave. The potassium ions can only go out one way. When the potassium channels located on the luminal side. The action of sodium-potassium pump causes you to secrete potassium ions, while you are reabsorbing na ions. You cannot separate them, this process of secretion, is regulated. Since k+ is important for establishing resting membrane potential, implications for excitable cells. When k+ levels get too high in the ecf the cells can depolarize. That can cause cells to be less capable of responding to capable signals.