KINE 2011 Lecture Notes - Endoplasmic Reticulum, Ryanodine Receptor, Cardiac Muscle Cell
29 Mar 2014
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Document Summary
Pacemaker membrane potential goes -60 to +5 ; 30 to -90 for musle membrane potential. The slowly rising line with the dotted blue is the pacemaker potential. As you get a slow rise in mem poten you hit threshold, you get a spike in the action potential when it comes down and it starts all over again. The slope of the line is going to determine the heart rate. Calcium is high outside the cell, and it moves inside the cell. When you stop calcium from going in , potassium is allowed to go out, membrane potential comes back to normal, and it restarts and goes over and over again. The closeness of this action potential that determine heart rate. The depolarization of the sa node leads to depolarization of the arterial muscle that leads to wave of depolarization travelling across the heart rate. Since these cardiac action potential don"t need any out put.
