Diseases of the Airway
Restrictive Disease : no change in resistance
Normal airway resistance ( air can move in and out easily)
-Problem is that lung cannot inflate as much (reduced lung capactity ; volume of air; LUNG can’t
expland as much.
Caused by diseases of
1. Pleura (including pneumothorax)
-Penomothorax can get better
2. Pulmonary Fibrosises (thickening of alveolar walls in the lung tissue)
-Lung is made of elastic spongy fibers that’s why it contracts and expands but it
becomes more non-elastic fibrous tissue in this pulmonary fibroses.
Cystic Fibroses is not the same ; it’s the thinking of mucusus that lines the alveoli
It does not have this connective tissues
-Problems with our nervous system (ALS,
-Problems with our muscles (polio, myasthenia gravis(stiff muscles), muscular
-Tieing a belt around a chest to breath is like RESTRICTIVE DISEASE. Obstructive is
like covering half your mouth.
-Movement of air (slower in obstructive) and (faster in resistive)
-Spirometer: device that measure air flow in and out of your mouth
Tidal Vol: normal volume of breathing in and out
Reserve Volume: Some air stays inside no matter what.
Know these formulas, and the graph.
The amount of air moved in/out of the alveoli
-expressed per minute
-minute ventilation (ml/min) air moving in and out of the mouth per minute
-Dot indicates that it’s a RATE (ml/min)
-V E minute ventilation
-The amount of air that moves in and out of lungs but that doesn’t predict how much gets in the alveoli ( that’s where gas exchange occurs)
-No all air that we breathe gets to our lungs.
-150ml is the air that is in the trachea that NEVER makes it out (dead space since it
doesn’t do anything) * but everybody has that*
-500ml you breath in it pushes the 150ml down into alveoli only 350ml goes into
-When you take in air you are not getting all NEW AIR. 150ml is always stuck down
VA= Alveolar Ventilation