KINE 3012 Lecture Notes - Lecture 30: Electrochemical Gradient, Angiotensin-Converting Enzyme, Extracellular Fluid
7 Apr 2018
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Ecf volume: has an important e ect on blood pressure, within that uid we need to maintain salt balance because water follows salt so if you maintain salt amount you maintain ecf uid volume. 3 major ways we can disrupt the balance in our body: drinking, sweating, hemorrhage. These receptors trigger a pathway that produces cyclic amp. Cyclic amp is the second messenger that stimulates these vesicles to move to the plasma membrane where they fuse with it and cause the insertion of the channels. This entire mechanism is fast acting since the channels already exist, they just need to be stimulated: so right when we introduce vasopressin, we start reabsorbing water. The reason we are taking in water molecules is because there is a hyper osmotic interstitium that was made by the loop of henle. This will lead to water moving into the interstitium. These vasopressin secreting neurons are the same ones that tell you you"re thirsty to drink.
