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KINE 3012 (22)
Tara Haas (22)
Lecture 8

Lecture 8 - Jan 25th.docx

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Kinesiology & Health Science
KINE 3012
Tara Haas

Page 44 - CO2 Transport - Just like oxygen, movement CO2 is the same. It is driven by partial pressure of the CO2 - CO2 has a much higher solubility coefficient(k), it gets dissolved at a much lower pressure - Don't remember numbers of amount of dissolved CO2 in other books. Use the one in notes. - CO2 + H2O H2CO3 *Carbonic acid* HCO3- + H+ *Carbonic acid split into 2 components* Page 45 - Breakdown from carbonic acid into its components when it's combined from H2O and CO2 - CO2 + H2O only occurs with the help of carbonic anhydrase catalyst - Same enzyme *Carbonic Anhydrase* can occur both ways *which is unique* - What determines the amount in the blood is the concentration of the molecules - Increase in CO2 will cause increase of Carbonic acid in the blood - We want to keep CO2 in the tissue low. In order to maintain this gradient, we create more carbonic anhydrase, then it changes to bicarbonate and hydrogen ion which has no pressure on the blood - CO2 is directly proportional to Carbonic acid - After CO2 is released into the alveoli and breathed out of the body, Carbonic acid will convert into CO2 + H2O - So to decrease the amount of CO2 in the blood, we can hyperventilate - Kidneys remove bicarbonate and hydrogen ions, failure of kidneys require us to hyperventilate to reduce them Extra Slides Page 8 - Cells have high CO2 concentration, higher pressure in the cells - Higher pressure than plasma, in order to reduce the pressure in plasma low, we have to breathe - Some of the CO2 binds with hemoglobin, which has no pressure - 75% of oxygen stays bind to hemoglobin - Bicarbonate is removed into the
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