KINE 3012 Lecture Notes - Lecture 17: Marfan Syndrome, Elastin, Coronary Circulation
3 Dec 2013
School
Department
Course
Professor
Document Summary
Aneurysm, low frequency event, people usually die of heart attack first. During old age, if you have higher blood pressure, the blood will try to find places to go. Due to weaker aortic wall, the blood breaks through the endothelial layer. Marfan syndrome *sometimes called spiderman syndrome because these individuals have exceedingly long limbs* It messes up the body"s ability to put together proteins. Difference between marfan syndrome and normal person, they both have elastin however marfan syndrome have a weaker aortic wall structure caused by genetic predisposition. Required to do a lot of work while not having enough oxygen. E. g. aorta 300mmhg while ventricle is 120mmhg, the heart does receive the oxygen that is within the chamber. Lv must be higher than the pressure in aorta in order to pump blood. Atherosclerosis plaque that gets stuck within artery walls. Makes the coronary arteries to get blood through.
