KINE 4010 Lecture Notes - Lecture 13: Lactate Dehydrogenase, Adipocyte, Alanine Transaminase

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The hydrogen ion coming from lactic acid is being buffered by this bicarbonate system and hydrase activity and making co2. This extra co2 is coming from the buffering of hydrogen ion, this is an important source of co2 that happens only when we must start to buffer hydrogen ion. And we breath it out and becomes part of the volume that we breath out. So, it is extra co2 which comes and adds to this volume that we breath out when we start producing lactic acid. Lactic breaks into two parts one is hydrogen ion which does its part and then the lactate part. The lactate part its dependent on the enzymes that metabolize it and they are m-ldh and h-ldh. M-ldh forms lactic acid in fast twitch muscles and they don"t have many mitochondria they rely on glycolysis and lactic acid. another one is lactate converting into pyruvate and it has high affinity for lactate.

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