KINE 4900 Lecture Notes - Lecture 10: Hemoglobin, Hyperinsulinemia, Low-Density Lipoprotein

• School: York University
• Department: Kinesiology & Health Science
• Course: KINE 4900
• Professor: Emilie Roudier

Document Summary

Diabetes- related to increase in adipose tissue and lack of exercise. It is an indicator for excess blood glucose. When there is a lot of glycated hemoglobin- there is increase in blood glucose. High caloric intake and no pa cause a strain on b calls to secrete more insulin. The demand to produce more insulin is to balance out the excess glucose and maintain normal glucose levels. The increase in insulin by the b call causes the b cell dysfunction and decrease its mass. This results in the increase in glucose and the reduction in insulin and leads to t2d. 2) insulin increases or decreases to keep the glucose levels the same. (maintain the glucose tolerance) In the graph, the ppl at high risk, progress from normal glucose tolerance to type2 go through igt before falling of the curve. 2nd graph- in this graph the decline in insulin sensitivity is not matched by the mutual (reciprocal) increase in insulin response.