NATS 1675 Lecture Notes - Lecture 4: Blood Transfusion, Antigen, Railways Act 1921

3 views2 pages
11 Nov 2016

For unlimited access to Class Notes, a Class+ subscription is required.

Rh Iopatiility Nov. , 4
- Coditio that affets a fetus he the fetus ad the other’s lood type are differet
- Oly the Rh lood type e’re oered aout here
- In explanation, opportunity to talk about immune system, antigens and antibodies
- Talking about blood groups: ABO blood
Blood Grouping Basics
Blood groups are determined genetically
Blood groups are identified by the presence or absence of a protein termed an antigen on
the surface of the Red Blood Cells (RBCs)
o Protein on surface of RBC is antigen protein that can stimulate immune response
o Antigens can fit into antibodies (also proteins)
o Protein molecules are characterized by having specific shapes (protein: shape)
o Many biological processes are controlled by shapes of interacting proteins
o Antigens on the surface of red blood cells have a specific shape
There are many groups of blood antigens, but the most commonly discussed are the ABO
group and the Rhesus (Rh) factor.
o O stands for zero, nothing there or Rhesus factor (Rh)
o Identified in the blood of Rhesus monkeys
o If you are A+, you have A antigens and Rh antigen
o A-, you lack the Rh group
o AB, both antigens
o B, type B antigens
o O, none O, Rh positive/negative
o Rh factor is independent of ABO blood grouping
The presence of one group of antigens does not affect the presence or absence of other
antigens, eg. One can be Group A and + for the RH factor. This means antigens for the A group and
the RH factor are both present on the RBCs.
Type AB+ Blood
Red blood cells do not have nuclei, throw it out before released in circulation for more surface
area to carry oxygen
Type AB+ blood type, RBC has A, B and Rh antigen (different shapes)
Blood Groupig Basis Cot’d
Antibodies: proteins designed to protect the body exist within the plasma portion of the
o Circulating within plasma are for wrong or opposite blood type
o If you are type A, you have type B antibodies
o If you are Rh negative, you have antibodies against Rh antigen
o You do’t hae atiodies agaist your own blood type but against the wrong blood
find more resources at
find more resources at
Unlock document

This preview shows half of the first page of the document.
Unlock all 2 pages and 3 million more documents.

Already have an account? Log in

Get access

$10 USD/m
Billed $120 USD annually
Homework Help
Class Notes
Textbook Notes
40 Verified Answers
Study Guides
1 Booster Class
$8 USD/m
Billed $96 USD annually
Homework Help
Class Notes
Textbook Notes
30 Verified Answers
Study Guides
1 Booster Class