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Lecture 14

NATS 1675 Lecture Notes - Lecture 14: Robert Crippen, Autosome, Chromosome


Natural Science
Course Code
NATS 1675
Robert Crippen

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NATS 1675 LECTURE #14 Chromosomal Abnormalities cont / Protein Synthesis
Professor : Robert Crippen
It is a diagram that shows the occurrence & appearance or phenotypes of a particular
gene/organism & its ancestors
There are 3 types of pedigrees : Autosomal inheritance, Sex-linked inheritance and
Autosomal recessive inheritance
On the Diagram:
When you see a square, it signifies male
When you see a circle, it signifies female
If the circle and square are shaded, they are affected by some disease
If we see a line joining the shapes, it means marriage or partnership
If there is a vertical line, it means the offspring has children
[Above] on the left, it will be the oldest child; on the right, it will be the youngest child. In
this particular situation, the parent has a son & 2 daughters
If there is an horizontal line [beside the child], it means they had a marriage/ partnership
Death of male or female =
Unspecified sex =
Thought Question:
Why dont they recommend the marriage/partnership between brother-sister & cousins?
Answer: There is a greater chance that if there is a recessive gene, the child will have the
unwanted recessive gene. If there is an unwanted recessive gene that runs along the family, it
wont be covered up by a dominant gene or other genes
Autosomal Inheritance
It refers to the inheritance of characteristics that are carried of the 22 pairs [in humans]
of autosomal chromosomes, not the sex chromosomes
We have 22 pairs of chromosomes & we all have it It is called autosomes
In autosomes, there is one pair that is called a sex chromosome & that determines
what our sex is [male or female]
Sex-linked Inheritance
It refers to the inheritance of characteristics that are normally carried on the X-
None of the genes on the Y-chromosome [males] is homologous to any of the genes on
the X-chromosome [females]
The Y-chromosome carries very little genetic information
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