NATS 4210 Lecture Notes - Lecture 6: Goose Bumps, Thermostat, Vasoconstriction

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Hypothalamus major thermoregulatory integrative center ( thermostat ) Animals have multiple thermoreceptors located in various regions of the body: 1) peripheral monitor skin temperature, 2) central in the hypothalamus and other brain regions as well as the abdominal organs. 3 subsets of neurons in the hypothalamus that are sensitive to changes in temperature. Most of the following are part of the family of trp (transcient receptor potential) Neuron population 1 (cold-sensitive: stimulates thermogenesis, vasoconstriction, and piloerection (raising the degree of the hair on the surface of the skin, shivering or non shivering mechanisms, more active when you"re cold. Neuron population 2 (warm sensitive: stimulates vasodilation and sweating, takes a lot of energy to turn water as liquid into gas. Neuron population 3 (warm sensitive: decreases thermogenesis, vasodialation and piloerection, population 2 + 3 work together to lower body temperature. On left side: skin temperature thermoregulation detected by peripheral thermoreceptors and sent to hypothalamus.

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