Interferon-Innate Immune Responses Against Viruses
Interferon: Innate Immune Responses Against Viruses
• Synthesized by virus-infected cells
• Binds to interferon receptor of nearby uninfected cells
• Induces them to eliminate viral genome (RNA) and black viral protein synthesis and
• Does not protect the original infected cell
• Does not prevent viruses from invading the protected cells
• Interferon is not virus-specific
o Synthesis in response to one virus will also protect against other viruses.
• Side effects
• Interferon as a drug- it’s not a very successful drug at this level
Specific or adaptive immunity
• A response to a specific molecule (antigen)
• The immune system can “remember” invaders and react more promptly to second
exposures to infection
o Only an exposure to the same antigen will activate this memory response.
• The specific immune system response distinguishes between self and non-self and
only reacts against non-self.
• Specific response
• Immunological memory
o Cellular (T cells) o Humoral (B cells)