HPV: infections vs. abnormalities
10, 000, 000
1, 400, 000
Having HPV mediated abnormality does not mean a woman will get cancer.
HPV and Cervical Cancer
HPV is the Primary Cause of Cervical Cancer
• HPV DNA can be found in nearly 100% of the cervical cancers.
• Approximately 30% of oral cancers in patients that lack the classical risk factors of
tobacco and alcohol abuse, are HPV positive
Epidemiology of Cervical Cancer insidecancer.org
• Poor routine health care for women.
Cervical Cancer is One of the Most Preventable Cancers
• With the appropriate screening and follow-up. • Vaccination
Cervical Cancer Screening and Prevention
• Prevented simply by screening
o PAP test
Looks for abnormal cells
• Cervical cancer is very rare in women who get regular PAP tests
How is a Pap test done?
• A small brush or spatula is used to collect cells from the cervix
• The sample I sent to the lab and the cells are examined under a microscope.
What will a Pap Test tell Us?
• If the cells in the cervix are…
o Minor cell changes of unknown importance, possibly unrelated to pre-cancer
o Moderate cell changes
o Severe cell changes
• Looks for the virus that causes the cell changes in the cervix
• DNA based assay
• More sensitive in determining presence of disease when used with Pap than Pap alone.
• Positive PAP and HPV results = objective risk indicator for the development of high-
grade cervical disease and cancer.
How often Does a Female Need a Pap Test?
• Until age 30: Every year from about 3 years after 1 sexual intercourse or by age 21,
whichever is first. • After a