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NATS 1670 (241)
Motti Anafi (197)

Lecture 53.docx

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Natural Science
NATS 1670
Motti Anafi

Influenza 1918 Spanish flu: killed 50-100 million people worldwide Influenza in the General Population • Infection rate: 10-20% in the general population • Typical symptoms o Fever, chills, headache, sore throat, cough, rhinitis  Mainly side effects from the recovery from the disease • Interferon and cytokines • Green line: secondary infection • Incubation period: 1-4 days • Most symptoms resolve in a week • However, complications such as a secondary bacterial infections kills many people every year Transmission • Person to person • Via respiratory droplets (most cases) • Sneezing coughing • Up to 1,000,000 virions per droplet • Direct contact (kids) Pneumonia and Influenza Mortality for 122 U.S Cities 15 century Italian scholars described The 1918 Spanish flu pandemic • Most well-known pandemic 1918-1919 o Approximately 50 million deaths worldwide Images from the 1918 Influenza Pandemic Why 1918 Influenza pandemic has killed a disproportionate number of young adults? • “cytokine storm” o An immune system that has over-reacted and is damaging the body, causing
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