NATS 1670 Lecture Notes - Chemotherapy, Integrase, Subtypes Of Hiv
10 Feb 2012
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Document Summary
Rna (diploid) 2 exact copies of rna, 2 genomes. Enzymes: that are not active but are simply there. Bound to rna and wait for rna to bind to cytoplasm in the cell and be activated. Protein coat: protects genome of virus because rna is highly subceptible to everything around and can be destroyed immediately. Lipid envelope: helps the virus carry certain proteins that can help the virus to get into the cell. Gp120 attachment protein: first protein to recognize the cell. Existing and potential drugs for aids are based on unique enzymatic activities of the hiv in hiv infected cells. The virus first recognizes 2 different receptors on the cell (cd4 molecule receptor found on helper t-calls, and co- receptor) Today we have several drugs which try to stop the virus from binding to the co-receptor. The genome of the virus is releases and the transcriptions process will begin, reverse transcriptase.
