PSYC 2240 Lecture 8: Lecture 8
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Bind to receptors found mostly in the spinal cord and periaqueductal gray area of the midbrain. Block the release of substance p (neuropeptides) endorphins. Group of chemicals that attach to opioid receptors. Blocking the release of neuropeptide of substance p (stronger pain) Placebo: a drug or other procedure with no pharmacological effect. Mechanisms of the body to increase sensitivity to pain: damage or inflamed tissue releases histamine, nerve growth factor, and other chemicals that increase the responses of nearby pain receptors. Certain receptors become potentiated after an intense barrage of painful stimuli leads to increased sensitivity or chronic pain later. Nonsteroidal anti-inflammatory drugs decrease pain =by reducing the release of chemicals from damaged tissue. (cid:271)(cid:396)ai(cid:374) diso(cid:396)de(cid:396)s su(cid:272)h as pa(cid:396)ki(cid:374)so(cid:374)"s disease a(cid:374)d hu(cid:374)ti(cid:374)gto(cid:374)"s disease (cid:374)ot o(cid:374)ly affe(cid:272)ts movement but also impair mood, memory and cognition. Causes: genetics: studies suggest early-o(cid:374)set pa(cid:396)ki(cid:374)so(cid:374)"s has a ge(cid:374)eti(cid:272) li(cid:374)k, ge(cid:374)eti(cid:272) fa(cid:272)to(cid:396)s a(cid:396)e o(cid:374)ly a s(cid:373)all fa(cid:272)to(cid:396) of late o(cid:374)set pa(cid:396)ki(cid:374)so(cid:374)"s disease (afte(cid:396) 50 years)