PSYC 3140 Lecture Notes - Haloperidol, Agranulocytosis, Mesolimbic Pathway

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Published on 18 Apr 2013
School
York University
Department
Psychology
Course
PSYC 3140
Professor
ABNORMAL PSYCH
LECTURE: FEB 26TH, 2013
TOPIC: SCHIZOPHRENIA
Final exam Monday April 15th → Rexall Center
Schizophrenia and the Nobel Prize
John Nash (answer)
Michael Smith
Arvid Carlsson
John Nash p. 375
Book and Movie “A Beautiful Mind”
Nobel prize in Economics – 1994 (almost homeless by this time)
Developed Mathematical Game Theory 1949 (age 21)
Later onset of schizophrenia
Schizophrenics → misinterpretations of staring for example not
exactly hallucinations
Age that it typically strikes people – late teens early twenties
Nash started with schizophrenia in his mid-late twenties
Michael Smith
Won Nobel Prize in Chemistry 1993
Struggled initially in school
B average as undergrad
Completed PhD in chemistry
Donations
Donated half of his prize to be put towards schizophrenia
(helped put schizophrenia on the map)
He also donated the other half to helping women be part of
learning science and math etc
He died of leukemia
Arvid Carlsson
Born in Uppsala, Sweden in 1923
Pharmacologist
Won Nobel Prize (co-winner) in 2000 for Medicine/Physiology
Developed the 'dopamine theory of schizophrenia'
Helped understand the role of dopamine in the development of
extra........
Should those with schizophrenia be considered to have a disability?
Majority of class says yes, 30% say no
Yes because it affects how they take part in daily functioning
Leading Causes of Disability ages 15-44 in Developed Regions
Both Sexes schizophrenia is number 4
Young Men – number 5
Young Women – number 2
p. 381 Positive Symptoms
Hallucinations – Voices commenting/voices conversing
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Delusions
Disorganized Behaviour
Disorganized thoughts and speech
Use head set to help them learn coping strategies because of their
auditory hallucinations (hear voices)
1) Voices Commenting – you are doing a good job
2) Hearing voices which are in conversation with each other – he is
doing a good job, no he isn't
PTSD – it could be accompanied by similar voice hearing
symptoms from being a victim
Hearing voices does not mean you are automatically
schizophrenic
Why positive symptoms?
These are things that are there that should not be present
Negative symptoms – things are not there that should be
Thematic Appercepton Test
Look at pic and make a story
Woman looking back at a man behind her
Schizophrenia answer – man comes behind a woman with a knife
and says she has to do what he says and she does but he still kills
her
There is no knife in the picture so it is coming from their
paranoid imagination
Example of Catatonic Behaviour
Waxy Flexibility – their movements are as if they are made out of wax.
Very stiff movements. This is quite rare. More frequent in 50's/60's. Do
not know why this has become rare now.
Negative Symptoms (p. 387)
Affective Flattening – monotone, expressionless in voice ( such as how a
lecturer speaks), normal speech has animation
Alogia – lacking in spontaneity of speech
Avolition – lacking in will power
The letter A in front of a word means not
Social Dysfunction
Impaired social skills – example: just walking up to someone in the
middle of a lecture and invading their space and just started a
conversation out of no where – picking the wrong time, too close to
person
Which of these problems are considered by family members to be most
common?
Hear voices
Has unusual beliefs
Lacks conversation
Has few friends (answer)
Problem behaviours identified by family members when their SCZ relative
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Document Summary

Final exam monday april 15th rexall center. Should those with schizophrenia be considered to have a disability: majority of class says yes, 30% say no, yes because it affects how they take part in daily functioning. Leading causes of disability ages 15-44 in developed regions: both sexes schizophrenia is number 4, young men number 5, young women number 2. Example of catatonic behaviour: waxy flexibility their movements are as if they are made out of wax. Do not know why this has become rare now. Which of these problems are considered by family members to be most common: hear voices, has unusual beliefs, lacks conversation, has few friends (answer) Problem behaviours identified by family members when their scz relative lives at home: most frequent/common, most difficult, has few hobbies, friends, underactive, lacks initiative, unusual beliefs, hear voices, does not take meds regularly, denies having an illness.

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