PSYC 4080 Lecture Notes - Lecture 9: Lobotomy, Autopsy, Basal Ganglia

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Test-type question which of the following was not used to treat schizophrenia prior to. 1950? (frontal lobotomy, insulin shock, chlorpromazine, barbiturates) answer: chlorpromazine. Dopamine abnormalities could arise from which of the following? (excess synthesis, excess release, excess receptors, other neurotransmitters) answer: all of the above. Antipsychotic is to tranquilizing as: chronic (long-term) is to acute. Da abnormalities are evident in: a minority of schizophrenia patients- a, a majority of patients, all patients, no patients. Side-effect theory holds that unpleasant motor symptoms develop because drugs cause da blockade, suppression, inhibition in the nigrostriatal tract. Notes: using medication na ve is a way to compare da receptor density due to chronic administration of antipsychotic medications, homovanillic acid is the by-product of da (there was no difference in the concentration in. Hva in csf in scz patients vs. controls) look at the effect size from last.

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