BIOSCI 106 Lecture Notes - Lecture 2: Fructose, Constipation, Succinic Acid
4 Sep 2013
School
Department
Course
Professor
Document Summary
Fructose is created when sucrose is cleaved by sucrase. Coenzymes or cofactors are small molecules which participate in the catalytic activity of enzymes. They are often identical or closely related to dietary components called vitamins which are essential but only in relatively small quantities. Vitamins are cofactors or can be converted to cofactors but not all cofactors are vitamins. Atp generated by cells not derived from vitamins. Not used in the reaction by the enzymes. A nucleotide based cofactor, phosphorylation of adp creating atp can be accomplished by substrate level phosphorylation and oxidative phosphorylation. There are other nucleotide triphosphates that can be used to drive energy dependent reactions. Requirement proportional to caloric intake eg fever, heavy exercise and high carb intake mean greater thiamine intake. Water soluble and heat liable, can be lost when foods are cooked. Malabsorption, malnutrition, alcohol and diarrhoea can contribute to thiamine deficiency.
