Class Notes (838,211)
New Zealand (288)
PHAL303 (2)
Lecture

Lecture 1 - Introduction to CNS.docx

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Department
Pharmacology
Course
PHAL303
Professor
Steve Kerr
Semester
Spring

Description
CNS:  Cerebral Cortex  Limbic System  Midbrain & brainstem  Cerebellum  Spinal cord Neuronal Ultrastructure:  Freeze-fracture microscopy  Immunohistochemistry  TEM and SEM Molecular Ultrastructure:  X-ray crystallography  Molecular modeling  Structure-activity relations (SAR) Molecular genetics:  Genetic modification / genetic engineering  Gene therapy  Genes as targets of drug therapy Defining a Neurotransmitter: 1. Must be present in presynaptic terminal 2. Must be released from the terminal following presynaptic action potential activity 3. Application of the transmitter to target cells must produce effects which are identical to those effects produced by presynaptic stimulation Neurotransmitters:  Synaptically released molecules which classically produce
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