BIOSCI 202 Lecture Notes - Lecture 3: Retrovirus, Murine Leukemia Virus, Repeat Unit

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Eukaryote genomes tend to be larger than prokaryotes. Eukaryote genomes vary about 5000 folds from the largest to the smallest. No relationship between genome size and phenotypic complexity. The number of genes varies considerably between prokaryotes and eukaryotes e. g. bacteria have 1,500 7,500 while eukaryotes range from 5,000 4,0000 genes. Eukaryotes genomes generally have a lower density of genes compared to prokaryotes e. g. human and other mammals have the lowest gene density. Most bacteria genomes consist of genes for proteins, trna or rrna with the remaining consisting of non- transcribed regulatory regions. Whereas, in eukaryotes the vast majority of dna neither encodes protein nor is transcribed to rna of known function. Human have 10,000x as much non-coding dna as bacteria. A classification of the different class of dna sequences types of dna in the human genome. Exons sequences that encode proteins (1. 5% in human) Introns intervening sequences that are not translated (5% in human)

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