PUBH-340 Lecture Notes - Lecture 4: Age Adjustment, Time 100

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The occurrence of disease: mortality and other measures of disease impact. Total # of deaths from all causes in 1 year / # of persons in the population at midyear 1,000. The numerator should ideally be restricted to deaths from that disease. # of individuals dying during a specified period of time after disease onset or diagnosis / # of individuals with the specified disease 100. In mortality rate, the denominator represents the entire population at risk of dying from the disease, including the people who have the disease and the ones who do. In case-fatality, the denominator is limited to those who already have the disease. It is a measure of the severity of the disease. Used to measure any benefits of a new therapy; as therapy improves, case-fatality would be expected to decline. # of deaths from a particular disease during a specific period of time / total deaths in that specific period of time 100.

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