BIO-1801 Lecture Notes - Lecture 21: Francis Crick, Thymine, Nitrogenous Base

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26 Apr 2017
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Chapter 11
DNA and RNA
Clicker Question; These meet the criteria for genetic material
genes: stretches of DNA found in chromosomes
Chromosomes
genes can be color coded
Nucleotides
are defined by their bases
message in DNA is the order or the bases (sequence) which is what the message is all
about
Genetic material must have:
information
replication
transmission
variation
genetic variation
Griffth’s Baterial Trasforatio
rough strains (r) without capsule are not fatal
smooth strains (S) with capsule are fatal
if mice are injected with heat killed type s, they survive
mixing live r with heat-killed s kills the mouse
transmission
something transformed and changed the bacteria
used 2 strains
one called r strain (rough) bc outside the bacteria is rough
s strain called virulent
Avery, MacLeod and McCarty
tried to figure out what transformed the bacteria into an virulent strain
Hershey and Chase and DNA
worked with viruses called phage
bacteriophage
attacks bacteria
this experiment showed that the genetic material is the reason things are
reproduced
Clicker Question: The experiments of Hershey showed:
showed that DNA is the genetic material
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