BIOL BC 1500x Lecture Notes - Lecture 6: Polysaccharide, Macrophage, Thymus

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Defends bodies (for animals and plants) from invasion by pathogens. Adaptive defenses/speci c defenses: reactions based on prior encounters with a speci c foreign object. Studying note: pay attention to owcharts and diagrams in textbook! Adaptive immune response: gets rid of speci c foreign objects. Must recognize what is invading, and what is part of the organism"s body. Antigen: usually a protein or a polysaccharide, anything that the immune system recognizes does not belong in the body, identi ed by antibodies. Antibodies: protein that identi es/binds to foreign material (antigen) by the antigenic determinant (aka epitope) Antigenic determinate: part of foreign invader that the antibody recognizes as foreign, antibodies are antigenic-determinate-speci c. Circulatory, lymphatic, and immune cells are closely related. Start as pluripotent stem cells: contain nearly complete genome but none of the genes are activated. From pluripotent, become either myeloid stem cells or lymphoid stem cells.

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