BIOL BC 1500x Lecture Notes - Lecture 8: Foldit, Protein Folding, Ribonucleotide
26 Aug 2016
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Biol bc1502 introduction to cell and molecular biology. Anfinsen"s dogma: final fold was dependent on the amino acid sequence, lowest energy state. Leventhal"s paradox: 10 amm 99 peptide bonds. Fold-it: protein folding takes computers way too long, + humans. Crowd sourcing: actually able to solve a number of important structures. Monomer nucleotides: nitrogenous base + sugar + 3 phosphate. Dna: hereditary of material of all living things (+ some virus) Rna: hereditary material in some viruses, also the intermediate between dna and protein in all cells, involved in catalyzing some reactions, some features make it more versatile than dna, nucleotide structure. Adenine: nitrogenous base, sugar, 3 phosphate groups, ribonucleotide (rna, oh, deoxy ribonucleotide (dna, h, adenine, guanine containing nucleotides are also important as energy currency/cell regulators a. i. Hydrogen bonding between nitrogenous bases of different nucleotides. Cg 3 hydrogen bonds: dna polymer. Discovery of dna as the hereditary material: johann friedrich miescher. Isolated nucleon from pus (contains mostly white blood cells)
