BIO 1305 Lecture Notes - Lecture 1: Human Genome Project, Transposable Element, Noncoding Dna
16 Dec 2017
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Document Summary
Genomics: the study of whole sets of genes and their interactions. Bioinformatics: the application of computational methods to the storage and analysis of biological data. Human genome project: mapping any genome to determine the complete nucleotide sequence of each chromosome. Whole-genome shotgun approach: used cloning and sequencing of dna fragments of randomly cut dna followed by assembly into a single continuous sequence. Metagenomics: dna from an entire group of species (metagenome) collected in an environmental sample is sequenced. Proteomics: the systematic study of full protein sets encoded by a genome. Systems biology: approach can be applied to define gene circuits and protein interaction networks; it aims to model the dynamic behavior of whole biological systems based on interactions among the system"s parts. Pseudogenes: former genes that have accumulated mutations and no longer produce functional proteins. Repetitive dna: sequences present in multiple copies in the genome.
