BIO 4307 Lecture Notes - Lecture 11: Glutamine, Gc-Content, Base Pair
Document Summary
Lecture 11: nucleic acids: chapter 33 all and 32 (555-63, examine chemical composition and physical characteristics, the nucleic acids are linear polymers built from similar units (nucleotides) connected end to end. Each monomer unit consists of a sugar, phosphate and a base. The sequence of bases is uniquely characterizing a nucleic acid and represents a form of linear information: dna and rna differ in two ways: It goes in the 5" to the 3" direction: the sugar- phosphate linkage is considered to be the backbone of the nucleic acids, note that each phosphodiester linkage possesses a negative charge and this is important. Because it allows or the repulsion of nucleophilic species that could cleave the backbone. The absence of a 2"-oh in dna increases this resistance. Bases: both nucleic acids consist of bases that vary in their arrangement, purine- adenine and guanine, pyrimidine- cytoside and thymine (dna) and uracil (rna, nucleotides and nucleosides.
