NSC 3356 Lecture Notes - Lecture 5: Ed50, Naproxen, Competitive Inhibition
Document Summary
Make a set of steps beginning with a precursor- transport it into the neuron and changing enzymatically into a ntrans- enclose it into a vesicle or even further metabolize it- So if we inactivate them with an antagonist we can enhance transmission. Due to genes that ultimately must do with this physiology. In that terminal with enzymes that break it down. Those systems must do with moods and long acting effects on organs: structure and function of ionotropic receptors. It is closed to a point to where an ion cannot close so it s not always airtight closed. This depends on the size of the ion for example ca+ is large so na and k might also pass as well: sometimes there are allosteric sites on the other subunits. Binding here can enhance the ion flux: other pores like gaba has a binding site called picrotoxin and when its bound it shuts it off/cannot get through, discovery of binding site.