NSC 3356 Lecture Notes - Lecture 3: Agonist, Partial Agonist, Inverse Agonist

• School: Baylor University
• Department: Neuroscience
• Course: NSC 3356
• Professor: jimpatton

Document Summary

Pharamcodynamics: receptors, the interaction of the r group with the phospholipid- protein (r-groups_ co-evolved with the lipid membrane and changed how the receptor worked. So changing the membrane layer can affect how the protein worked: from 30s to know when can specify the aa sequence of the receptors/pumps and be able to tell its 3 or 4 structure. Also, with better technology for gene sequencing we can find what genes encode for it. Amazing all we need is the 1 structure: example. Androgen sensitivity due to a genetic variation that is different enough to change the 3 structure of the protein in testosterone so the receptors are inactive/not functional. Think about how a change in neurochemistry can change the way the see themselves. Restricted space in the middle of the lumen that is not completely shut: what"s lining in the inside is positively charged side chains that repel the na.