BIOL 3210 Lecture Notes - Lecture 13: Decarboxylation, Electrophile, Valine
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Something that should be intuitive, but she wants to point out: if km is the same, the intercept on the x-axis is the substrate concentration (-1/km) The lines will fan out from that one point on the x-axis. Telling us because this is on the mcat. -----this information will not be on the test friday------ Catalytic mechanisms: general acid-base catalysis the enzyme helps pick up protons or delete protons, covalent catalysis covalent intermediate with an enzyme. Nucleophile they are looking for nuclei because they are negatively charged: important ones: negatively charged oxygen, deprotonated hydroxyl, deprotonated cysteine (sulfhydryl group), carbanion, uncharged amine group, imidazole ring, hydroxide ions. Electrophile is something that is electrically positive, that wants electrons: important ones: carbon of a carbonyl, phosphorous within a phosphate, you don"t need to memorize this list. Curved arrows depict the flow of electrons. Functional groups present in enzymes: don"t memorize this, but look and be familiar.
