BIOL 4330 Lecture Notes - Lecture 23: Basal Lamina, Solution, Colloid

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Lecture 23: solutes in the filtrate what is excreted from the kidney will depend on how the kidney goes through its processes (filtration, reabsorption, secreted, ho(cid:449) (cid:373)u(cid:272)h (cid:449)e"re goi(cid:374)g to see (cid:449)ill depe(cid:374)d o(cid:374) those 3 features. Controlling local bp within the glomerulus: remember, blood flow is proportional to pressure gradient, opposition is resistance, arterioles can either hold afferent or efferent (dilation or constriction, blood flow, pressure gradient. Lecture 23: affected by arterial pressure, affected by total blood volume, affected by co and sv, vis(cid:272)osity (cid:449)o(cid:374)"t really (cid:272)ha(cid:374)ge so (cid:373)u(cid:272)h, we deal mostly with resistance due to radius resistance is primary driver of gfr. Increase salt-->increase gfr > increase flow by releasing adenosine to bind alpha 1 receptors on afferent arteriole and cause vasonconstrction, increase resistance of the arteriole and bring the gfr down. Na increase passes the mdc, increases gfr: mdc secretes adenosine causing vasoconstriction of afferent so renal blood flow comes down and.

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