PSYC 1032 Lecture Notes - Lecture 25: Monoamine Oxidase A, Antisocial Personality Disorder, Conscientiousness

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Gene x environment interactions: remember q: resilience why some people are more affected than others, serotonin 5ht. Major stressors: fired, breakup, death, homelessness: 15% had 4 or more, dependent variables 4 mental health measures @ age 26- depression related. Friend/family reports of depression: x axis - # of stressful life events (0-4+, each graph has one of the 4 dvs, graph a self-reported depression symptoms. 3 lines each line corresponds to a genotype. When people have 0, 1 stressful event it is not a function of what your genes are. But when you have 2+ you start to see a spread according to genotypes. More significantly to be depressed if you have genotype s/s: genes interact with ability to regulate your emotion. Gene x environment interactions, 2: q: why do some kids who are maltreated grow up to be fairly stable, whereas other grow up and exhibit antisocial behavior, early maltreatment + stress dysregulated norepinephrine (ne), serotonin (5-

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